21 wins & 78 nominations
- 2001 Winner American Comedy Award
- Funniest Male Performer in a TV Series (Leading Role) Network, Cable or Syndication
- 1999 Nominee American Comedy Award
- Funniest Male Performer in a TV Special (Leading or Supporting) Network, Cable or Syndication
For the 5th Anniversary Special. - 1996 Nominee American Comedy Award
- Funniest Male Performer in a TV Series (Leading Role) Network, Cable or Syndication
- 1995 Winner American Comedy Award
- Funniest Male Performer in a TV Special (Leading or Supporting) Network, Cable or Syndication
- 1994 Winner American Comedy Award
- Funniest Male Performer in a TV Series (Leading Role) Network, Cable or Syndication
- 2015 Nominee Primetime Emmy
- Outstanding Variety Talk Series
Shared with: Barbara Gaines · Matt Roberts · Jude Brennan · Rob Burnett · Maria Pope · Nancy Agostini · Jerry Foley · Kathy Mavrikakis · Sheila Rogers · Brian Teta · Michael Buczkiewicz - 2010 Nominee Primetime Emmy
- Outstanding Children's Nonfiction Program
Shared with: Christina Delfico · Lisa Lax · Nancy Stern Winters · Rob Burnett · Andrew Ames · Kevin Clash - 2009 Nominee Primetime Emmy
- Outstanding Variety, Music or Comedy Series
Shared with: Barbara Gaines · Maria Pope · Jude Brennan · Rob Burnett · Jerry Foley · Matt Roberts · Eric Stangel · Justin Stangel · Sheila Rogers - 2009 Nominee Primetime Emmy
- Outstanding Writing for a Variety, Music or Comedy Series
Shared with: Eric Stangel · Justin Stangel · Michael Barrie · Jim Mulholland · Steve Young · Tom Ruprecht · Lee H. Ellenberg · Matt Roberts · Jeremy Weiner · Joe Grossman · Bill Scheft · Robert Borden · Frank Sebastiano - 2008 Nominee Primetime Emmy
- Outstanding Individual Performance in a Variety or Music Program
- 2015 Nominee People's Choice Award
- Favorite Late Night Talk Show Host
- 2014 Nominee People's Choice Award
- Favorite Late Night Talk Show Host
- 2013 Nominee People's Choice Award
- Favorite Late Night Talk Show Host
- 2009 Nominee People's Choice Award
- Favorite Talk Show Host
- 2001 Nominee TV Guide Award
- Talk-Variety Star of the Year
- 2009 Nominee WGA Award (TV)
- Comedy/Variety - (Including Talk) Series
Shared with: Eric Stangel · Justin Stangel · Michael Barrie · Jim Mulholland · Steve Young · Tom Ruprecht · Lee H. Ellenberg · Matt Roberts · Jeremy Weiner · Joe Grossman · Bill Scheft · Robert Borden · Frank Sebastiano - 2002 Nominee WGA Award (TV)
- Comedy/Variety (Including Talk) - Series
Shared with: Eric Stangel · Justin Stangel · Gerard Mulligan · Joe Toplyn · Michael Barrie · Jim Mulholland · Steve Young · Gabe Abelson · Carter Bays · Craig Thomas · Chris Harris · Tom Ruprecht · Bill Scheft · Lee H. Ellenberg - 2001 Nominee WGA Award (TV)
- Comedy/Variety (Including Talk) - Series
Shared with: Bill Scheft · Carter Bays · Chris Harris · Eric Stangel · Gabe Abelson · Gerard Mulligan · Jim Mulholland · Joe Toplyn · Justin Stangel · Lee H. Ellenberg · Michael Barrie · Rob Burnett · Rodney Rothman · Steve Young · Tom Ruprecht · Craig Thomas - 2000 Nominee WGA Award (TV)
- Comedy/Variety (Including Talk) - Series
Shared with: Rodney Rothman · Gerard Mulligan · Bill Scheft · Michael Barrie · Jim Mulholland · Joe Toplyn · Eric Stangel · Justin Stangel · Steve Young · Gabe Abelson · Carter Bays · Craig Thomas · Jon Beckerman · Chris Harris · Tom Ruprecht · Beth Sherman · Jeff Boggs · David Javerbaum · Rob Burnett
- 2002 Winner TV Prize
- Best Foreign TV Personality - Male (Bästa utländska manliga tv-personlighet)
- 2013 Nominee OFTA Television Award
- Best Male Performance in a Fiction Program
- 2012 Nominee OFTA Television Award
- Best Male Performance in a Fiction Program
- 2010 Nominee OFTA Television Award
- Best Male Performance in a Fiction Program
- 2009 Winner OFTA TV Hall of Fame
- Actors and Actresses
- 2017 Winner Mark Twain Prize
- Mark Twain Prize for American Humor
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