- Helen Virginia Horton was born in Chicago, Illinois, to Frances Katherine (Stewart) and Walter Clark "Bud" Horton. She was married to James Hamish Thomson, of Inverkeithing, Fife, Scotland. Their granddaughter is actress Lily James. On her father's side, Helen had Colonial American roots in New England. On her mother's side, she had Scottish ancestry, by way of Canada.
- Famously provided the voice of "Mother," the Nostromo space ship's omniscient computer in Alien (1979).
- Horton was a regular on The Benny Hill Show (1969) in the 70s and 80s usually playing Benny's wife in many skits.
- Mother of actor/musician Jamie Thomson.
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